规格：50µL/100µL
货号：PN0157
价格：1350元/50µL；2200元/100 µL
全称 | Endoglin |
别名 | Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1
|
抗体来源 | Rabbit polyclonal |
交叉反应 | Human |
产品应用 | IHC： 1:500~1:1000 IF： 1:500~1:1000 |
理论/观测到的分子量 | 71 kDa / 90 kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | A synthesized peptide derived from human CD105 |
亚 型 | IgG |
纯化方法 | Affinity purification |
Uniprot ID | |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disµLphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascµLar endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascµLar development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.
