规格：100μl
价格：3000元/100μl
数据表
| UniProt | P12830 |
| Mol Weight | 135kDa |
| Alternative Names | Arc1;Cadherin 1;CAM 120/80;CD324;CDHE;E-Cad/CTF3;ECAD;Epithelial cadherin ;LCAM;Uvomorulin;CDH1; |
| Immunogen | A synthesized peptide derived from human E Cadherin |
| Storage | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Description | CDH1 a single-pass type I membrane protein, and calcium dependent cell adhesion proteins. It is a ligand for integrin alpha-E/beta-7, and it colocalizes with DLG7 at sites of cell-cell contact in intestinal epithelial cells. |
Applications
| Reactivity | Human |
| Application | WB,IHC,ICC/IF,FC |
| Recommended dilution | WB 1:5000~1:10000 IHC 1:100~1:500 ICC/IF 1:100~1:500 FC 1:500 |
| All lanes use the Antibody at 1:6W dilution for 1 hour at room temperature. |
| Immunofluorescent analysis using the Antibody at 1:50 dilution. |
| Western blot analysis of E-cadherin expression in MCF7 cell lysate. |
| Immunohistochemical analysis of paraffin-embedded human colon cancer, using E Cadherin Antibody. |
| SLC25A22 promotes proliferation and metastasis by activating MAPK/ERK pathway in gallbladder cancer. -Cancer Cell International |
| EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. -Cancer Letters |
| Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1. -ONCOLOGY LETTERS |
