规格：50µL/100µL
货号：PN0142
价格：1350元/50µL；2200元/100 µL
全称 | Amyloid-beta precursor protein |
别名 | ABPP, APP, N-APP, Soluble APP-alpha, S-APP-alpha, C99, APP-C99, Abeta42, Abeta40, Beta-APP40, C83, APP-C59, Amyloid intracellµLar domain 59, APP-C57, Gamma-CTF(50), C31, App, Aβ40, Aβ42, A beta 40，beta Amyloid 40 |
抗体来源/类型 | Rabbit Polyclonal |
交叉反应 | Mouse,,Rat |
产品应用 | IHC/IF：1;400-1:1000 |
理论分子量 | 86kDa |
细胞定位 | 细胞膜，细胞质 |
性 状 | Liquid |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse Aβ40 |
亚 型 | IgG |
纯化方法 | Affinity purification |
Uniprot ID | P12023 |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms—particµLarly Aβ40—without increasing Aβ42 levels.
