规格：50µL/100µL
货号：PN00742
价格：1350/50µL；2200元/100 µL
全称 | glutathione peroxidase 4 (phospholipid hydroperoxidase) |
别名 | GSHPx 4, GPx-4, GPx 4, EC:1.11.1.9, EC:1.11.1.12 |
抗体来源 | Mouse |
克隆类型 | Monoclonal |
交叉反应 | Human, Mouse, Rat, Pig, Rabbit, Chicken, Zebrafish, Hamster, Dog (predicted:Human, Mouse, Rat, Pig, Chicken, Bovine, Goat, Sheep, Duck) |
产品应用 | WB : 1:1000-1:4000 IHC : 1:1000-1:4000 IF/ICC : 1:400-1:1600 |
理论分子量 | 20-23kDa |
细胞定位 | 细胞质 线粒体 |
性 状 | Liquid |
浓 度 | 1000ug/ml |
免 疫 原 | GPX4 fusion protein Ag30650 |
亚 型 | IgG |
纯化方法 | Protein A purification |
Uniprot ID | |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Store at -20°C. Stable for one year after shipment. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
GPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about 20KDa and 22KDa, respectively. GPX4 is a monomer,but it has a tendency to form higher mass oligomers (PMID:17630701). It presents primarily in testis.
