规格：50µL/100µL
货号：PN0200
价格：1350元/50µL；2200元/100 µL
全称 | Collagen alpha-1(I) chain |
别名 | COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human;Mouse;Rat |
产品应用 | WB 1:500-1:1000 IHC/IF 1:500-1:1500 |
理论/实际分子量 | 139kDa / 120-140 kDa/200-250 kDa |
细胞定位 | 细胞质 细胞外基质 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Human COL1A1 |
亚 型 | IgG |
纯化方法 | Affinity-chromatography |
Uniprot ID | P02452 |
缓 冲 液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存条件 | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.
