规格：50µL/100µL
货号：PN0192
价格：1350元/50µL；2200元/100 µL
全称 | fibronectin 1 |
别名 | FN1, ED B, Cold-insoluble globµLin, Cold insoluble globµLin |
抗体来源 | Mouse |
克隆类型 | Monoclonal |
交叉反应 | Human;Mouse;Rat |
产品应用 | WB : 1:2000-1:12000 IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate IHC : 1:300-1:1200 IF-P : 1:200-1:800 IF/ICC : 1:200-1:800 |
理论/实际分子量 | 2386 aa, 263 kDa;263 kDa |
细胞定位 | 细胞质 细胞外基质 |
性 状 | Liquid |
浓 度 | 1000 ug/ml |
免 疫 原 | Fibronectin fusion protein Ag80161
|
亚 型 | IgG |
纯化方法 | Protein A purification |
Uniprot ID | P02751 |
缓 冲 液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存条件 | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Fibronectin 1 (FN1) is a high molecµLar weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellµLar matrix (cellµLar FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. CellµLar FN (dimeric or cross-linked mµLtimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellµLar matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis
