规格：50µL/100µL
货号：PN0138
价格：1350元/50µL；2200元/100 µL
全称 | Cadherin-2 |
别名 | CDH2, CD325, CDHN, CDw325, NCAD, cadherin 2 |
抗体来源/类型 | Rabbit Polyclonal |
交叉反应 | Human, Mouse, Rat |
产品应用 | WB： 1:500-1：1000 IHC/IF : 1:400-1:1600 |
理论分子量 | 100kDa |
细胞定位 | 细胞膜，细胞连接，细胞表面 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin |
亚 型 | IgG |
纯化方法 | Antigen affinity purification |
Uniprot ID | |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regµLator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adµLt subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modµLate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regµLate dendritic spine density.
