规格：50µL/100µL
货号：PN0065
价格：1350元/50 µL ,2000元/100 µL
全称 | Phospho-Akt(Ser473) Antibody |
别名 | AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha; |
抗体来源 | Rabbit Monoclonal |
交叉反应 | Human, Mouse,, Rat |
产品应用 | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 |
理论分子量 | 60kDa |
细胞定位 | 细胞质，细胞核，细胞膜 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | A synthesized peptide derived from human Phospho-Akt(Ser473) |
亚 型 | IgG |
纯化方法 | Affinity-chromatography |
Uniprot ID | |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.
