规格：50µL/100µL
货号：PN0054
价格：2600元/50 µL ,5100元/100 µL
抗体来源 | Rabbit |
克隆类型 | Monoclonal |
交叉反应 | Mouse, Rat, Human |
产品应用 | WB 1:2000 IHC 1:1000 IP 1:80 |
理论分子量 | 31kDa |
细胞定位 | 细胞质 |
性 状 | Liquid |
浓 度 | 1.519-1.577 mg/ml |
免 疫 原 | RecRecombinant fragment. This information is proprietary to Abcam and/or its suppliers. |
亚 型 | IgG |
纯化方法 | Protein A purified |
Uniprot ID | |
缓 冲 液 | pH: 7.2 |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regµLatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes.
