规格:50µL/100µL
货号:PN0213
价格:1350元/50 µL ,2200元/100 µL
全称 | bone gamma-carboxyglutamate (gla) protein |
别名 | BGLAP, Osteocalcin, BGP, Bone Gla protein, Gamma-carboxyglutamic acid-conta |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat( Pig, Canine) |
产品应用 | IHC : 1:50-1:500 IF/ICC : 1:200-1:800 FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspensi |
理论分子量 | 100 aa, 11 kDa |
细胞定位 | 分泌型 |
性 状 | Liquid |
浓 度 | 500 ug/ml |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse Osteopontin |
亚 型 | IgG |
纯化方法 | Antigen affinity purification |
Uniprot ID | P02818 |
缓 冲 液 | pH: 7.2,Preservative: 0.01% Sodium azide,Constituents: 59% PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine) |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Osteocalcin is a small, highly conserved molecµLe associated with mineralization of bone matrix. Osteocalcin is specifically expressed in osteoblasts and is the most abundant non-collagenous protein in bone. It regµLates the dynamics of new bone formation and bone resorption by interaction with vitamin D, and by influencing the differentiation of osteoblasts. Osteocalcin is also involved in the posttranslational targeting of vitamin K-dependent gamma-carboxylation, which controls blood coagµLation.