规格:50µL/100µL
货号:PN0125
价格:1350元/50µL;2200元/100 µL
全称 | CD11b Antibody |
别名 | CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6;ITGAM |
抗体来源 | Rabbit |
克隆类型 | Monoclonal |
交叉反应 | Mouse, Rat, Human |
产品应用 | WB 1:1000-1:2000 IHC 1:100-1:200 ICC/IF 1:50-1:200 IHF 1:50-1:200 |
理论分子量 | 127/170kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 具体以批次为准 |
免 疫 原 | A synthesized peptide derived from human CD11b |
亚 型 | IgG |
纯化方法 | Affinity-chromatography |
Uniprot ID | |
缓 冲 液 | pH: 7.2,Preservative: 0.01% Sodium azide,Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granµLocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b.