规格:50µL/100µL
货号:PN0126
价格:1350元/50µL;2200元/100 µL
全称 | Anti-CD11C |
别名 | CD11C; SLEB6; ITGAX |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, Human |
产品应用 | WB:1:500-1:1000 IHC/IF:1:50-1:200 |
理论分子量 | 128kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 批次间有差异 |
免 疫 原 | Recombinant fusion protein containing a sequence corresponding to amino acids 146-342 of ITGAX |
亚 型 | IgG |
纯化方法 | Affinity purification |
Uniprot ID | |
缓 冲 液 | pH: 7.2,Preservative: 0.01% Sodium azide,Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimµLated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.