规格：50µL/100µL
货号：PN0127
价格：1350元/50µL；2200元/100 µL
全称 | CD86 Antibody |
别名 | CD86;B7-2;B70;CD28LG2;LAB72;MGC34413; CTLA4 counter receptor B72; CLS1; Ly58; MB7; |
抗体来源 | Rabbit |
克隆类型 | Monoclonal |
交叉反应 | Mouse, Rat, Human |
产品应用 | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50 |
理论分子量 | 38/70kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 批次间有差异 |
免 疫 原 | A synthesized peptide derived from human CD86 |
亚 型 | IgG |
纯化方法 | Affinity-chromatography |
Uniprot ID | |
缓 冲 液 | pH: 7.2，Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Receptor involved in the costimµLatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimµLation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regµLator of T-cell activation.
