规格：50µL/100µL
货号：PN0164
价格：1350元/50µL；2200元/100 µL
全称 | MicrotubµLe-associated protein 2 |
别名 | MAP2, MAP2A, MAP2B, MAP2C, microtubµLe associated protein 2
|
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse;Rat |
产品应用 | IHC 1:500-1:3000 ICC/IF 1:500-1:3000 |
理论/预测分子量 | 200kDa/70, 280 kDa |
细胞定位 | 细胞质，细胞骨架，细胞突起 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse MAP2 |
亚 型 | IgG |
纯化方法 | Affinity purification |
Uniprot ID | |
缓 冲 液 | pH: 7.2，Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
The proteins of this family are thought to be involved in microtubµLe assembly, which is an essential step in neuritogenesis. MAP2 serves to stabilize microtubµLes (MT) growth by crosslinking MT with intermediate filaments and other MTs. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
