规格:50µL/100µL
货号:PN0134
价格:1350元/50µL;2200元/100 µL
全称 | Nestin |
别名 | Nes, Nestin |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, Human(predicted: Human, Mouse,Zebrafish ) |
产品应用 | WB:1:500-1:1000 IHC:1:200-1:800 IF: 1:200-1:800 |
理论分子量 | 177kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 600ug/ml |
免 疫 原 | Peptide |
亚 型 | IgG |
纯化方法 | Antigen affinity purification |
Uniprot ID | |
缓 冲 液 | pH: 7.2,Preservative: 0.01% Sodium azide,Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Nestin, also named as NES and Nbla00170, is a class VI intermediate filament protein expressed in stem cells of the central nervous system (CNS) but not in mature CNS cells. Its expression is used extensively as a marker for neural lineage cells derived from human embryonic stem (hES) and induced pluripotent stem (iPS) cells. Nestin is also expressed in non-neural stem cell popµLations such as pancreatic islet progenitors and hematopoietic progenitors. Nestin can be detected as 220-240 kDa and 240-280 kDa. Studies point toward nestin heavy posttranslational modifications as possibly serving particµLar functions in podocytes and in a few other particµLar cell types